| 翻訳と辞書 |
| Protein-DNA interaction ： ウィキペディア英語版 |
Protein–DNA interaction
Protein–DNA interactions are when a protein binds a molecule of DNA, often to regulate the biological function of DNA, usually the expression of a gene. Among the proteins that bind to DNA are transcription factors that activate or repress gene expression by binding to DNA motifs and histones that form part of the structure of DNA and bind to it less specifically. Also proteins that repair DNA such as uracil-DNA glycosylase interact closely with it.
In general, proteins bind to DNA in the major groove; however, there are exceptions.
Protein–DNA interaction are of mainly two types, either specific interaction, or non-specific interaction.
==Design==
Designing DNA-binding proteins that have a specified DNA-binding site has been an important goal for biotechnology. Zinc finger proteins have been designed to bind to specific DNA sequences and this is the basis of zinc finger nucleases. Recently transcription activator-like effector nucleases (TALENs) have been created which are based on natural proteins secreted by ''Xanthomonas'' bacteria via their type III secretion system when they infect various plant species.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Protein–DNA interaction」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|